Improve Battery life of a wireless keyboard & mouse
1] Turn off the devices when not in use
The first and foremost tip to remember is to turn the wireless devices (keyboard and mouse) off when not in use. Doing so improves the battery life of a wireless keyboard to a great extent. You can use the manual turn-off method to switch off your mouse/keyboard when you are done for the day. If you observe closely, there is a small on/off switch at the bottom of your wireless mouse that you can use to manually turn it off. (UPDATE based on comments: Not all devices may have this switch). Using this button is important because even though your wireless mouse is left idle for a few minutes or hours, it is not switched off completely. They go to sleep when there is no activity noticed but wake up immediately as soon as they are pushed aside or moved around inside your bag or in your hand—and this movement can use a lot of power! If you do not have a good memory and often forget to turn off the devices you can set a reminder, here is a nice tip courtesy Labnol. This is a bit tricky, but works! Just visit this page and enter some text in the empty ‘WRITE HERE’ field. The tool will convert the text into an MP3. Then, hit the ‘Listen’ button and the computer will speak your words in a natural-sounding female voice.
Next, download the MP3 file, go to Control Panel > Change system Sounds > Exit Windows, and browse to the downloaded file to set it as a reminder for turning off your mouse and keyboard. Do the same for ‘Windows Log off’ – that’s it!
2] Keep keyboard away from large metal surfaces
A keyboard does not have an On/Off switch. The keyboard should be placed closer to the computer, within 30 cm (12 in), and away from interference from other electrical or wireless devices, especially speakers and cell phones. Moreover, it should not be used on large metal surfaces.
3] Keep Mouse & Keyboard at the same level surface
If you are using both, the mouse and the keyboard simultaneously make sure they are within 100 cm (39 in) of the computer and on the same level surface.
4] Use Mouse on light-colored surfaces
Always use the mouse on a light-colored surface or preferably on an opaque surface. Using the mouse over a dark-colored surface such as a black or dark blue surface can cause the battery to drain faster. Also, never use the mouse on a glass surface, because a tracking sensor in a wireless mouse uses more power on such surfaces causing the depletion of the battery at a much faster rate.
5] Use keyboard more where necessary
Use the keyboard where necessary! The more you move your mouse, the more power it uses. That’s because it has a laser which consumes more power. So, If you know some great keyboard shortcuts and can use them in place of mouse cursor use them. This will greatly reduce the work pressure on your mouse thereby helping you get more life out of your mouse batteries.
6] Restrict Mouse-intensive activities
Spend less time doing mouse-intensive activities, such as browsing the Internet and when replacing batteries, use alkaline batteries. Although AA batteries aren’t highly expensive, I would recommend getting rechargeable batteries and a charger. It costs much less than getting AA batteries replaced quite often.
7] Check the Keyboard/mouse battery-level indicator
When on a Windows Desktop, hover the mouse over the mouse or the keyboard battery-level indicator in the System Tray.
Green – indicates a full battery.Yellow – indicates the battery is half full.Red – indicates it is time to change the battery.
There is a nice document at HP.com that you may want to read.
8] Place Wireless devices always near the computer
When the wireless devices are not in use, always store them nearby your computer. There is no magic formula for improving the battery life of a wireless keyboard and mouse drastically but keeping these tips in mind will surely help you to improve the same to some extent. These tips to Conserve Battery Power and Extend or Prolong Battery Life in Windows may also interest you.